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Frequently asked questions

This is where we get your questions answered by a diabetes expert from one of the finest institutions in the world, Guy's King's and St Thomas' Schools of Medicine. If you have any more questions you would like answered, please post them in the forum.

What is Diabetes?

What are the different types of Diabetes?

What causes Diabetes?

How many people are affected by the different types of Diabetes?

What are the warning signs I should look out for?

How is diabetes Diagnosed?

How does Diabetes progress?

Does Diabetes run in families?

Can Diabetes occur in younger people?

What treatment is available?

What is being done to find a cure or prevention?

What should I do if I feel overwhelmed by my diagnosis?

What are clinical drug trials?

How do I handle my feeling of anger, loneliness and depression?

Why should I join a support group?

 

What is Diabetes?

Normally the body strictly controls the level of sugar in the blood. Most of the food we eat is broken down into sugar (glucose) and then used by the body. In diabetes the body can no longer regulate the level of sugar in the blood and can not use the glucose properly. Click here for more information.

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What are the different types of Diabetes?

There are three main types of diabetes:

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Type 1 diabetes

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Type 2 diabetes

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Gestational diabetes

 

Type 1 diabetes is an autoimmune disease. An autoimmune disease results when the body's system for fighting infection (the immune system) turns against a part of the body. In diabetes, the immune system attacks the insulin-producing beta cells in the pancreas and destroys them. The pancreas then produces little or no insulin. Someone with type 1 diabetes needs to take insulin daily to live.

            Type 1 diabetes accounts for about 5 to 10 percent of diagnosed diabetes in England & the United States. Type 1 diabetes develops most often in children and young adults, but the disorder can appear at any age. Symptoms of type 1 diabetes usually develop over a short period, although beta cell destruction can begin years earlier.

Symptoms include increased thirst and urination, constant hunger, weight loss, blurred vision, and extreme fatigue. If not diagnosed and treated with insulin, a person can lapse into a life-threatening diabetic coma, also known as diabetic ketoacidosis (Click for more information).

 

The most common form of diabetes is type 2 diabetes. About 90 to 95 percent of people with diabetes have this type. This form of diabetes usually develops in adults age 40 and older and is most common in adults over age 55.  It is, however, becoming increasing common in younger populations. It is most common among African Americans, American Indians, Hispanic Americans, people with weight problems and people with a family history of diabetes.

            When type 2 diabetes is diagnosed, the pancreas is usually producing enough insulin, but, for unknown reasons, the body cannot use the insulin effectively (a condition called insulin resistance). After several years, insulin production decreases. The result is the same as for type 1 diabetes--glucose builds up in the blood and the body cannot make efficient use of its main source of fuel.

            The symptoms of type 2 diabetes develop gradually. They are not as sudden in onset as in type 1 diabetes. Some people have no symptoms. Symptoms may include fatigue or nausea, frequent urination, unusual thirst, weight loss, blurred vision, frequent infections, and slow healing of wounds or sores.

            

Gestational diabetes develops only during pregnancy. Like type 2 diabetes, it occurs more often in African Americans, American Indians, Hispanic Americans, and people with a family history of diabetes. Though it usually disappears after delivery, the mother is at increased risk of getting type 2 diabetes later in life.

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What causes Diabetes?

For type 1 diabetes, scientists do not know exactly what causes the body's immune system to attack the beta cells, but they believe that both genetic factors and environmental factors, possibly viruses, are involved. In type 2 diabetes, although the exact cause is unknown, there is a prominent link with obesity (being overweight). About 80 percent of people with type 2 diabetes are overweight. Type 2 diabetes is often part of a metabolic syndrome that includes obesity, elevated blood pressure, and high levels of blood lipids. Unfortunately, as more children become overweight, type 2 diabetes is becoming more common in young people.

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How many people are affected by the different types of Diabetes?

In the UK the risk of developing type 1 diabetes by the time you are 20 is 3-4/1000 people. Around 5% of middle-aged and older populations are affected by type 2 diabetes. Diabetes and its complications overall account for more than 10% of the gross NHS budget.

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What are the warning signs I should look out for?

Click here for an throughout explanation

1. Chest pain

2. Leg pain

3. Changes in vision

4. Raging thirst

5. Frequent urination

6. Foot ulcers

7. Weight loss

8. Tiredness

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How is diabetes Diagnosed?

Click here for an throughout explanation

  1. Random blood sugar (glucose). This is not very accurate but is most convenient for the patient. Diabetes can only be diagnosed if the blood sugar is very high (above 15 mmol/L is diagnostic)

  2. Fasting glucose. This is where the patient will not have eaten for at least 8 hours before the blood test. This test is reasonably accurate (above 7.0 mmol/L is diagnostic).

  3. Oral Glucose tolerance test. This is the most accurate method of diagnosis, but is usually only required for a minority of patients. The patient is fed a carbohydrate diet (including mainly starchy dishes) for three days leading up to the test, and is then fasted for 8 hours before the test. At the test, the patient is given 200g of glucose and the blood sugar is monitored every 15 minutes (above 11.1 mmol/L is diagnostic).

 

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How does Diabetes progress?

Too much sugar in the blood for a long time causes diabetes problems. Over time, this results in damage to blood vessels leading to heart disease, stroke, blindness, kidney failure, impotence, circulatory problems and nerve damage. The disease can also complicate pregnancy and increase the risk of birth defects. Diabetes problems can be scary, but there is a lot you can do to prevent them or slow them down. See the treatment section for advice as to what you can do.

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Does Diabetes run in families?

There is very strong evidence that type 2 diabetes runs in families (genetic link). This evidence has been obtained from studies in twins and families. There is some family links in type 1 diabetes but this evidence is not as strong.

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Can Diabetes occur in younger people?

The peak age for type 1 diabetes is around 14 years old, although it can occur later in life, even up to the mid 30s. Type 2 diabetes usually develops in adults age 40 and older and is most common in adults over age 55. However, as more and more children become overweight it is becoming increasingly common in the younger populations.

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What treatment is available?

The best form of treatment is prevention! If this is not possible then we try to make the body behave as it would in health, by stabilising the blood sugar. The ways in which we do this are discussed further in the treatment section.

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What is being done to find a cure or prevention?

Diabetes is recognised as a very important condition for its global impact and as a consequence, much scientific research is being conducted to make advances in this condition. In recent years, advances in diabetes research have led to better ways to manage diabetes and treat its complications. Major advances include:

 

 

Evidence that intensive management of blood glucose reduces and may prevent development of diabetes complications.

 

The development of a quick-acting insulin analog.


Better ways to monitor blood glucose and for people with diabetes to check their own blood glucose levels.

Development of external insulin pumps that deliver insulin, replacing daily injections.

Laser treatment for diabetic eye disease, reducing the risk of blindness.

Successful transplantation of kidneys and pancreas in people whose own kidneys fail because of diabetes.

Better ways of managing diabetes in pregnant women, improving chances of successful outcomes.

New drugs to treat type 2 diabetes and better ways to manage this form of diabetes through weight control.

Promising results with islet transplantation for type 1 diabetes reported by the University of Alberta in Canada.

Evidence that people at high risk for type 2 diabetes can lower their chances of developing the disease through diet and exercise.

                  Researchers continue to search for the cause or causes of diabetes and ways to prevent and cure the disorder. Scientists are looking for genes that may be involved in type 1 or type 2 diabetes. Some genetic markers for type 1 diabetes have been identified, and it is now possible to screen relatives of people with type 1 diabetes to see if they are at risk.
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What should I do if I feel overwhelmed by my diagnosis?

This is a perfectly natural feeling and it should be discussed with people who you feel comfortable with, including your family, friends, and GP/nurse. For more information please see my section on coping with diabetes.

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What are clinical drug trials?

New drugs are constantly being developed to help us to control diabetes and its complications more efficiently. When these drugs have been developed then need to be tested for their effectiveness and safety. Patients are then asked if they would like to join a trial where these drugs are tested; during this time the patients are closely monitored and the benefits weighed alongside the side effects. These trials take place many years before drugs are released in order to assess their safety thus you have access to the latest medications. If you are interested in taking part in these trials, or would like more information, ask your hospital specialist for advice.

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How do I handle my feeling of anger, loneliness and depression?

Some people experience a range of emotions when they are told they have diabetes. Again this is a perfectly natural experience and it should be discussed with people who you feel comfortable with. For more information please see my section on coping with diabetes.

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Why should I join a support group?

Diabetes creates many challenges in your daily life, and a support group allows you to hear how others have coped or are coping with similar situations. Support groups are safe places to talk openly about difficult issues and feelings. And you may find that other group members will become a great source of comfort and encouragement. To find a support group near you, get in contact with you local GP or your community nurse, where you will be able to get more information. Share your experiences in the forum.

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This site was last updated 04/14/02