The ICRU recommend that a dosimetric precision of 3% (1 s.d.) and 3 mm is necessary to achieve local tumour control whilst avoiding normal tissue complications.
Our premise: Standardised measurements and theoretical extrapolation must be used in combination for the highest dosimetric precision.
Conventional RTP uses measurements relating to dose, performed under standardised conditions, as a first approximation to the dose in the patient.
Measured data form the bounding conditions for the distribution of dose in more complex circumstance.
Conventional planning algorithms are based on simplistic representations of the radiation transport enabling easy manipulation of formula to respect bounding conditions.